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Old 12-13-2009, 05:00 PM   #1
Rucker
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Default Steroids can raise LDL: Tocotrienols can lower LDL Cholesterol

Dear Asylum Members,


There are many different forms of Vitamin E. However, they aren’t all created equal.


The two main categories, tocotrienols and tocopherols are divided into four sub-categories each; alpha, beta, delta, and gamma. Tocotrienols are far superior to tochopherols when it comes to cardiovascular health benefits. These benefits have been proven in multiple studies and lab tests.


One study was done to show the reduction of LDL cholesterol levels from tocotrienol supplementation. After only 60 days of tocotrienol treatment, subjects showed an average decline of 23, 30, and 42% in serum total lipids, total cholesterol, and LDL cholesterol, respectively. (1) In the present investigation tocotrienols mediated a reduction of LDL cholesterol levels from an average of 179 mg/dl to 104 mg/dl. (1)





In comparison to other lipid lowering agents, tocotrienols offer many positive side effects. Most of the lipid lowering agents, currently in use in the treatment of dyslipidemia, have a host of negative side effects. In contrast, dietary tocotrienols are Vitamin E complex and have effective lipid lowering property in addition to their potent antioxidant activity.(1)


So I’ve established that tocotrienols have powerful cardiovascular health benefits. But even on this four headed beast that is tocotrienols, one head is high above the rest in this regard – Gamma-tocotrienols are dominantly superior.


In a heads up study between alpha tocotrienol and gamma tocotrienol it was proven that gamma-tocotrienol exhibits a 30-fold greater activity toward inhibiting cholesterol production compared to alpha-tocotrienol in HepG2 cells in vitro. (2)


In conclusion, gamma tocotrienols provide far more benefit to cardiovascular health than any other tocotrienol or tocopherol. At 52mg per serving, Primordial Performances Toco-8 boasts the highest gamma tocotrienol content.




Jim Benvie,
Primordial Performance Marketing


Questions?


Phone – 1-800-568-2924
Email - info@primordialperformance.com
Visit - Primordial Performance

References –
1. The therapeutic impacts of tocotrienols in type 2 diabetic patients with hyperlipidemia.
Baliarsingh S, et al.
Atherosclerosis 182(2):367-74. (2005)
2. Hypocholesterolemic activity of synthetic and natural tocotrienols.
Pearce BC, et al.
Journal of Medicinal Chemistry 35(20):3595-606 (1992)
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Old 12-13-2009, 07:39 PM   #2
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Questions?
Yes, one. Its in a powder form right and not encapsulated? So how are you managing to stop the oxidation of the CoQ10, the tocotrienols, and the tocopherols? Despite that it looks like a nice mix just don't at all see how you are preventing degridation.
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Old 12-13-2009, 08:34 PM   #3
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Yes, one. Its in a powder form right and not encapsulated? So how are you managing to stop the oxidation of the CoQ10, the tocotrienols, and the tocopherols? Despite that it looks like a nice mix just don't at all see how you are preventing degridation.
If you keep the product out of direct sunlight and in a dark cool place like the label recommends, the product will meet label claims for at least a year.

We recommend storing it in the fridge if you want it to last longer than that.

-Eric
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Old 12-15-2009, 09:42 PM   #4
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If you keep the product out of direct sunlight and in a dark cool place like the label recommends, the product will meet label claims for at least a year.

We recommend storing it in the fridge if you want it to last longer than that.

-Eric


Um, you sure? I've use CoQ10 before and once those vials are opened the're pretty much done for. Made the mistake one time of leaving some on a lab table for too long. In a few hours it went from the nice orange powder to a thick sticky brown tar at room temperature. The stuff does not like oxygen.

We are actually required to dispose of it once we use it, can't restore any of it even if kept refriderated and resealed well. Same thing with the vitamin Es with the exception of alpha tocopherol. Although I'm really not a fan of just using straight alpha tocopherol at all.

So any chance in the future you'll be coming out with blister packs or something like that?
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Old 12-16-2009, 01:42 PM   #5
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Um, you sure? I've use CoQ10 before and once those vials are opened the're pretty much done for. Made the mistake one time of leaving some on a lab table for too long. In a few hours it went from the nice orange powder to a thick sticky brown tar at room temperature. The stuff does not like oxygen.

We are actually required to dispose of it once we use it, can't restore any of it even if kept refriderated and resealed well. Same thing with the vitamin Es with the exception of alpha tocopherol. Although I'm really not a fan of just using straight alpha tocopherol at all.

So any chance in the future you'll be coming out with blister packs or something like that?
Sounds like you’re dealing with something hygroscopic? What vials of CoQ10 are you talking about?

A lot of vendors will up play the sensitivity of certain nutrients to oxygen. They do it with resveratrol all the time. But we can have that stuff exposed to atmospheric oxygen all day long, get it tested, and it still passes a 98-99% purity test.

-Eric
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Old 12-28-2009, 08:16 PM   #6
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Sounds like you’re dealing with something hygroscopic? What vials of CoQ10 are you talking about?

A lot of vendors will up play the sensitivity of certain nutrients to oxygen. They do it with resveratrol all the time. But we can have that stuff exposed to atmospheric oxygen all day long, get it tested, and it still passes a 98-99% purity test.

-Eric
I will look up the exact specs on the CoQ10 we use when I get back to work. I'm currently on paternity leave. (Yes, we have it. Yes, excuse to get out of work and still get paid.)

It is often over exagerated as to how quickly reseveratrol will oxidize. I think they do this because of how hard they are trying to push it as an anti-oxidant even though none of its usefull properties are because of that. Eh, most people don't have a clue with they are buying supplements though.
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Old 12-28-2009, 08:37 PM   #7
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You guys can now check out Toco-8 for only $23.96 during our new years sale. Get the best supplement deals of the year right now.
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Old 12-29-2009, 02:11 PM   #8
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Solid info there sir. Ive been reading up on it lately and its about that time to give it a try.
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Old 01-04-2010, 07:35 PM   #9
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Solid info there sir. Ive been reading up on it lately and its about that time to give it a try.
sounds good man. sale is good for another 48 hours
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Old 06-04-2010, 05:44 PM   #10
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http://www.ocregister.com/articles/t...min-brain.html
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